Hopx-2A-DreERT2

Nomenclature

C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc

Cat. NO.

NM-KI-190035

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Hopx

Synonyms

Hod; Hop; Ob1; Obl; Hdop; Toto; Cameo; AI848177; AW490897; 1110018K11Rik; 1200015P04Rik; 2300002F06Rik

NCBI ID

74318

MGI ID

1916782

Ensembl ID

ENSMUSG00000059325

Pubmed

Hopx

Human Ortholog

HOPX

Model Description

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.
Research Application：Dre recombinase tool

Validation Data

image.png

Fig. 1 DreERT2-mediated recombination in the lung of HopxDreERT2/+；R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in alveolar epithelial cells after tamoxifen treatment. T1a (green) is the marker gene known to be expressed in the adult lung solely by the alveolar type I epithelial cell. (Documented in the following reference.)


Publications

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more