Cdh1-2A-DreERT2

Nomenclature

C57BL/6Smoc-Cdh1em3(2A-DreERT2)Smoc

Cat. NO.

NM-KI-190031

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Cdh1

Synonyms

Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649

NCBI ID

12550

MGI ID

88354

Ensembl ID

ENSMUSG00000000303

Pubmed

Cdh1

Human Ortholog

CDH1

Model Description

A 2A-DreERT2 expression cassette was knocked into the Cdh1 gene stop codon site via CRISPR/Cas mediated recombination.
Research Application：Dre recombinase tool

Validation Data

image.png

Fig. 1 DreERT2-mediated recombination in the liver of Cdh1DreERT2/+；R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in the liver after tamoxifen treatment. Cdh1 gene encodes E-cadherin(E-CAD), a calcium-dependent adhesion  molecule that expressed primarily in epithelial cells. (Documented in the following reference.)


Publications

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

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