Ncr1-2A-Cre

Nomenclature

C57BL/6Smoc-Ncr1em2(2A-iCre)Smoc

Cat. NO.

NM-KI-190027

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ncr1

Model Description

A 2A-iCre expression cassette was knocked into the Ncr1 gene stop codon site.
Research Application:Cre recombinase tool

Validation Data

Ncr1-(2A-iCre).png

Fig1 Cre-mediated recombination in NK cells derived from spleen and peripheral blood of Ncr1-(2A-iCre);Rosa26 tdTomato mice.

Ncr1-2A-iCre-1.png


Fig. 2: Detection of tdTomato (red) in some cells of the skin, kidney, submandibular gland(SMG) and brain drived from Ncr1icre/+; Rosa26tdTomato/+ mice. 

Ncr1-2A-iCre-2.png

Fig. 3 Detection of tdTomato (red) in various tissues of Ncr1icre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in some cells of skin, kidney, liver, thymus, spleen, submandibular gland(SMG), brain, pancreas, colon, intestine, brown fat, testis and epididymis. But tdTomato expression can not be observed in the lung, heart or muscle. (For more detailed information please contact our technical advisor.)


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