Lyz2-2A-CreERT2

Nomenclature

C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc

Cat. NO.

NM-KI-18018

Strain State

Repository Live

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Gene Summary

Gene Symbol
Lyz2

Synonyms

Lys; Lzm; Lzp; Lysm; Lyzs; Lyzf2; Lzm-s1; AI326280

NCBI ID

17105

MGI ID

96897

Ensembl ID

ENSMUSG00000069516

Pubmed

Lyz2

Human Ortholog

LYZ2

Model Description

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
Research Application：Cre recombinase tool

Validation Data

lyz2-creERT2.png

Fig1 Evaluation of CreERT2 recombination in Lyz2 Cre+/-;R26 tdT+/- mice.

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