Pdx1-2A-Cre
Nomenclature
C57BL/6Smoc-Pdx1em(2A-Cre)1Smoc
Cat. NO.
NM-KI-225082
Strain State
Repository Live
Gene Summary
Gene Symbol
Pdx1
Model Description
2A-Cre expression cassette was knocked into the Pdx1 gene .
Validation Data
Fig1. Cre mediated recombination in pancreasof Pdx1Cre/+;Rosa26tdTomato/+ mice.
The white dashed line indicates the islets of langerhans.
Fig2. Cre mediated recombination in brunner's glands of Pdx1Cre/+;Rosa26tdTomato/+ mice.
Fig3. Detection of tdTomato(red) in various tissues of of Pdx1Cre/+;Rosa26tdTomato/+ mouse. The tissues of double-positive mice were cryosectioned and directly examined, revealing expression in the following organs: pancreas, lung, small intestine, kidney, colon;A few cells expressing it were also identified in the liver, adrenal gland, muscle, thymus, subcutaneous tissue;Tissues that unexpressed include:brain, retina, heart, stomach, salivary glands, brown fat, spinal cord, spleen, testis, epidermis, pituitary gland.
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