Ndufs4-KO

Nomenclature

C57BL/6Smoc-Ndufs4em1Smoc

Cat. NO.

NM-KO-201311

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Ndufs4

Synonyms

C1-18k; 6720411N02Rik

NCBI ID

17993

MGI ID

1343135

Ensembl ID

ENSMUSG00000021764

Pubmed

Ndufs4

Human Ortholog

NDUFS4

Model Description

Exon 2 of Ndufs4 gene was deleted to generate Ndufs4 knockout mice.

Disease Connection

Leigh disease

Phenotype(s)

MGI:5451011

Reference(s)

Quintana A, Zanella S, Koch H, Kruse SE, Lee D, Ramirez JM, Palmiter RD, Fatal breathing dysfunction in a mouse model of Leigh syndrome. J Clin Invest. 2012 Jul 2;122(7):2359-68

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