Lrrc10-KO

Nomenclature

C57BL/6Smoc-Lrrc10em1Smoc

Cat. NO.

NM-KO-201002

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Lrrc10

Synonyms

Hrlrrp， Serdin1， D330003I11Rik

NCBI ID

237560

MGI ID

2448063

Ensembl ID

ENSMUSG00000060187

Pubmed

Lrrc10

Human Ortholog

LRRC10

Model Description

Exon 1 of Lrrc10 gene was deleted to generate Lrrc10 knockout mice.

Disease Connection

Dilated Cardiomyopathy

Phenotype(s)

MGI:5905195

Reference(s)

Brody MJ, Hacker TA, Patel JR, Feng L, Sadoshima J, Tevosian SG, Balijepalli RC, Moss RL, Lee Y, Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS One. 2012;7(12):e51621

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