Lmna-c.C1827T

Nomenclature

C57BL/6Smoc-Lmnaem1(G609G)Smoc

Cat. NO.

NM-KI-200284

Strain State

Repository Live

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Gene Summary

Gene Symbol
Lmna

Synonyms

Dhe

NCBI ID

16905

MGI ID

96794

Ensembl ID

ENSMUSG00000028063

Pubmed

Lmna

Human Ortholog

LMNA

Model Description

These mice carry a G609G mutation of Lmna gene.

Disease Connection

Progeria

Phenotype(s)

MGI:5806144

Reference(s)

Lee JM, et al., Modulation of LMNA splicing as a strategy to treat prelamin A diseases. J Clin Invest. 2016 Apr 1;126(4):1592-602

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