Hyal1-KO

Nomenclature

C57BL/6Smoc-Hyal1em1Smoc

Cat. NO.

NM-KO-200990

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Hyal1

Synonyms

Fus2， Hya1， Nat6， Hyal-1

NCBI ID

15586

MGI ID

96298

Ensembl ID

ENSMUSG00000010051

Pubmed

Hyal1

Human Ortholog

HYAL1

Model Description

Exon 2 of Hyal1 gene was deleted to generate Hyal1 knockout mice.

Disease Connection

Mucopolysaccharidosis Ix

Phenotype(s)

MGI:3797579

Reference(s)

Martin DC, Atmuri V, Hemming RJ, Farley J, Mort JS, Byers S, Hombach-Klonisch S, Csoka AB, Stern R, Triggs-Raine BL, A mouse model of human mucopolysaccharidosis IX exhibits osteoarthritis. Hum Mol Genet. 2008 Jul 1;17(13):1904-15

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