Dmp1-KO

Nomenclature

C57BL/6Smoc-Dmp1em1Smoc

Cat. NO.

NM-KO-200634

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Dmp1

Synonyms

PP， AG1， Dmp， DMP-1， AV020965

NCBI ID

13406

MGI ID

94910

Ensembl ID

ENSMUSG00000029307

Pubmed

Dmp1

Human Ortholog

DMP1

Model Description

Exon 4-6 of Dmp1 gene was deleted to generate Dmp1 knockout mice.
Research Application：Research on the degradation of ECM proteoglycans and extracellular matrix

Disease Connection

Autosomal Recessive Hypophosphatemic Rickets

Phenotype(s)

MGI:5694692

Reference(s)

Zhang R, Lu Y, Ye L, Yuan B, Yu S, Qin C, Xie Y, Gao T, Drezner MK, Bonewald LF, Feng JQ, Unique roles of phosphorus in endochondral bone formation and osteocyte maturation. J Bone Miner Res. 2011 May;26(5):1047-56

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