F8-KO(2)

Nomenclature

C57BL/6Smoc-F8em3Smoc

Cat. NO.

NM-KO-200608

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
F8

Model Description

F8-KO(2) mice (Stock No.NM-KO-200608)carry a knockout allele derived from the targeted deletion of exon 1-26. While F8-KO mice (Stock No.NM-KO-00012) carrying the exon 16-19 deletion.
Research Application:Hemophilia A;HEMA

Disease Connection

factor VIII deficiency

Validation Data

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Fig1. Analysis of activated partial thromboplastin time (APTT) in the F8 knock-out mice. The coagulation time in F8-KO(2) (NM-KO-200608) was significantly longer than wild-type, and there was no obvious difference in coagulation time between F8-KO(NM-KO-00012)and F8-KO(2) (NM-KO-200608).



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