Mdk-KO

Nomenclature

C57BL/6Smoc-Mdkem1Smoc

Cat. NO.

NM-KO-200359

Strain State

Repository Live

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Gene Summary

Gene Symbol
Mdk

Synonyms

MK; Mek

NCBI ID

17242

MGI ID

96949

Ensembl ID

ENSMUSG00000027239

Pubmed

Mdk

Human Ortholog

MDK

Model Description

Exon 3-4 of Mdk gene was deleted to generate Mdk knockout mice.
Research Application：Therapeutic antibody target

Disease Connection

Schizophrenia

Phenotype(s)

MGI:3579532

Reference(s)

Ohgake S, Shimizu E, Hashimoto K, Okamura N, Koike K, Koizumi H, Fujisaki M, Kanahara N, Matsuda S, Sutoh C, Matsuzawa D, Muramatsu H, Muramatsu T, Iyo M, Dopaminergic hypofunctions and prepulse inhibition deficits in mice lacking midkine. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Apr 30;33(3):541-6

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