KPC(2)
Nomenclature
C57BL/6Smoc-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
Cat. NO.
NM-KI-220014
Strain State
Repository Live
Gene Summary
Gene Symbol
Trp53
Gene Symbol
Kras
Gene Symbol
pdx1
Model Description
Trp53-LSL-R270H, Kras-LSL-G12D were crossed with Pdx1-Cre-Tg to generate KPC mice. While KPC mice function similarly to KPC(2) mice, for more detailed information please contact our technical advisor.
Research Application：Spontaneous pancreatic tumor
*Literature published using this strain should indicate: KPC(2) mice (Cat. NO. NM-KI-220014) were purchased from Shanghai Model Organisms Center, Inc..
Disease Connection
pancreatic carcinoma
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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