hDPP4

Nomenclature

C57BL/6Smoc-Dpp4em1(DPP4)Smoc

Cat. NO.

NM-HU-190042

Strain State

Repository Live

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Gene Summary

Gene Symbol
Dpp4

Synonyms

Cd26; THAM; Dpp-4

NCBI ID

13482

MGI ID

94919

Ensembl ID

ENSMUSG00000035000

Pubmed

Dpp4

Human Ortholog

DPP4

Model Description

The endogenous mouse Dpp4 gene was replaced by human DPP4 gene.
Research Application：MERS infection research

Validation Data

image.png

Fig1. Detection of hDPP4 (CD26) expression in HO hDPP4 KI mice by FACS. 

image.png

Fig2. Detection of human DPP4 (A) and mouse DPP4 (B) expression in plasma by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

Publications

Isolation and characterization of a pangolin-borne HKU4-related coronavirus that potentially infects human-DPP4-transgenic mice
References：Nature Communications

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