Neil1-KO

Nomenclature

C57BL/6Smoc-Neil1em1Smoc

Cat. NO.

TBD

Strain State

Developing

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Gene Summary

Gene Symbol
Neil1

Synonyms

NEH1， Nei1， 2810450N13Rik

NCBI ID

72774

MGI ID

1920024

Ensembl ID

ENSMUSG00000032298

Pubmed

Neil1

Human Ortholog

NEIL1

Model Description

Exon 2-3 of Neil1 gene was deleted to generate Neil1 knockout mice.

Disease Connection

Abdominal Obesity-Metabolic Syndrome

Phenotype(s)

MGI:3620065

Reference(s)

Vartanian V, Lowell B, Minko IG, Wood TG, Ceci JD, George S, Ballinger SW, Corless CL, McCullough AK, Lloyd RS, The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1864-9

Obesity

Phenotype(s)

MGI:3620067

Reference(s)

Vartanian V, Lowell B, Minko IG, Wood TG, Ceci JD, George S, Ballinger SW, Corless CL, McCullough AK, Lloyd RS, The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1864-9

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