SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Thpotm1(hTHPO)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000062
Research Application：Cytokine humanization model；drug screening
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Strain Name：BALB/cAnSmoc-Tnfsf15em1(hTNFSF15)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220602
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Strain Name：C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200004
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Strain Name：C57BL/6Smoc-Tnfrsf23em(hTNFRSF10C)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-230344
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Strain Name：C57BL/6Smoc-Tnfsf14tm1(hTNFSF14)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225069
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Strain Name：C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000064
Research Application：Asthma research；drug screening
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Strain Name：C57BL/6Smoc-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200269
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Strain Name：NOD.Cg-PrkdcscidIl2rgem1SmocIl15em1(hIL15)Smoc
Strain State：Repository Live | Cat. NO.：GM-NVG-210001
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：NOD-PrkdcscidIl2rg-Tg(pCMV-hIL34-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-220433
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(pCAG-FRT-loxp-stop-loxp-hCD63-copGFP-6xHis-WPRE-polyA-FRT)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200044
Research Application：Exosome tracing model
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