hIL2RG/hIL2RB

Nomenclature

C57BL/6Smoc-Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc

Cat. NO.

NM-HU-210354

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
IL2RB

Synonyms

p70; CD122; IL15Rbeta; Il-2Rbeta; IL-15Rbeta; Il-2/15Rbeta

NCBI ID

16185

MGI ID

96550

Ensembl ID

ENSMUSG00000068227

Pubmed

IL2RB

Human Ortholog

IL2RB

Gene Symbol
IL2RG

Synonyms

gc; p64; [g]c; CD132; gamma(c)

NCBI ID

16186

MGI ID

96551

Ensembl ID

ENSMUSG00000031304

Pubmed

IL2RG

Human Ortholog

IL2RG

Model Description

hIL2RG(NM-HU-200007) was crossed with hIL2RB(NM-HU-2000055) to generate hIL2RG/hIL2RB mice.
Research Application：inmmue therapy；drug screening

Validation Data

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Fig1. Detection of hCD122 expression in hIL2RG/hIL2RB dKI mice.

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Fig2. Detection of hCD132 expression in hIL2RG/hIL2RB dKI mice.

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Fig3. Detection of immune phenotyping in peripheral blood and spleen in hIL2RG/hIL2RB dKI mice.

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