Ins2-C96Y

Nomenclature

C57BL/6Smoc-Ins2em3(C96Y)Smoc

Cat. NO.

NM-KI-190096

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ins2

Synonyms

Mody; Ins-2; InsII; Mody4; AA986540

NCBI ID

16334

MGI ID

96573

Ensembl ID

ENSMUSG00000000215

Pubmed

Ins2

Human Ortholog

INS2

Model Description

These mice carry a p.C96Y mutation of Ins2 gene.
Research Application：Diabetes related.

Disease Connection

Diabetes

Phenotype(s)

MGI:3583904

Reference(s)

Yoshioka M, et al., A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes. 1997 May;46(5):887-94

Validation Data

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Fig.1 The Basic Symptoms of Ins2-(C96Y) Mouse Compared with Its WT Litter Mate

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Fig.2 Body Weight of Ins2-(C96Y) Mouse Compared with Its WT Litter Mate

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Fig.3 Blood Glucose Level of Ins2-(C96Y) Mouse Compared with Its WT Litter Mate

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Fig.4 Water Intake of Ins2-(C96Y) Mouse Comparedwith Its WT Litter Mate

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Fig.5 Food Intake of Ins2-(C96Y) Mouse Compared with Its WT Litter Mate

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